Introduction

Welcome to the November D'Arcy Wellness Clinic Health Newsletter, where we hope to provide you with information that will make a difference to your health, through complementary and integrated therapies and natural medicines.

Very best wishes to you and your health.
Geoff D'Arcy Lic. Ac., D.O.M.

Acupuncture Study of the month: Osteoarthritis of the knee

A major study published in October gives confirms the medical benefits of acupuncture. Researchers say the therapy may help reduce the need for patients with arthritis to take anti-inflammatory drugs, which can have significant side effects.

It was studied by Dr. Claudia Witt of the University Medical Centre, Berlin, Germany, and colleagues, who recruited 3,553 patients with chronic pain due to osteoarthritis of the knee or hip.

The patients were divided into three groups; one randomly assigned to 15 sessions of acupuncture over three months, one randomly assigned to standard treatment then acupuncture for three months, and a large group given acupuncture (who did not consent to randomisation).

Acupuncture in addition to routine care showed significant improvements in symptoms and quality of life compared with patients who received routine care alone.

The improvement in symptoms continued after the treatment had ended. Following this study, German doctors and health insurers may recommend that the cost of acupuncture is reimbursed via state health insurance.

Arthritis & Rheumatism, Vol. 54, November 2006, pp. 3485-93, 3375-77.

Herb of the Month: Broccoli Sprouts

An amazing compound found in 3-7 day old broccoli sprouts, Sulforaphane glucosinolate (SGS) can protect us against cancer.Sulforaphane increases the body's own defense system against carcinogens. Cells in the body contain a family of detoxification enzymes (Phase 2 enzymes) that neutralize cancer-causing chemicals as well as free radicals before they damage DNA and initiate cancer.
"Chemoprotection is a deliberate effort to increase the body's defense systems against chemicals, including carcinogens, that can lead to disease," according to John Hopkins University Professor Dr. Talalay. "Chemoprotection may lower a person's risk of developing cancer by building up the body's own defenses".

Broccoli sprouts are a concentrated source of cancer-fighting sulforaphane.

Positive research is coming in, for a wide range of CANCER PROTECTION cancers, Bladder, Breast, Colon, Liver, Lung, Prostate, Skin.

BLADDER CANCER
Scientists at Ohio State University published a study that showed compounds from broccoli were able to decrease progression of cancer in lines of bladder cancer cells from humans and mice.

1. The role of c-Jun in the AP-1 activation induced by naturally occurring isothiocyanates Food Chem Toxicol. 2005 Sep;43(9):1373-80.Li J, Yao S, Zhang Y.
doi:10.1016/j.fct.2005.03.011

2. Dietary isothiocyanates inhibit the growth of human bladder carcinoma cells
J Nutr. 2004 Aug;134(8):2004-10Tang L, Zhang Y. PubMed ID: 15284390

3. Isothiocyanates in the chemoprevention of bladder cancer
Curr Drug Metab. 2004 Apr;5(2):193-201.Tang L, Zhang Y.
PubMed ID: 15078196

BREAST CANCER

1.Broccoli sprouts: An exceptionally rich source of inducers of enzymes that protect against chemical carcinogens (#) Proc. Natl. Acad. Sci. USA, Vol. 94, pp. 10367-10372, September 16, 1997.
Jed W. Fahey, Yuesheng Zhang, and Paul Talalay PubMed ID: 9294217

2. Inhibition of benzo[a]pyrene- and 1,6-dinitropyrene-DNA adduct formation in human mammary epithelial cells by dibenzoylmethane and sulforaphane (#)
Cancer Letters 2000 July 3; 155(1):47-54.Singletary K, MacDonald C.
PubMed ID: 10814878 Proc. Natl. Acad. Sci. USA, Vol. 94, pp. 10367-10372, September 16, 1997.Jed W. Fahey, Yuesheng Zhang, and Paul Talalay
PubMed ID: 9294217

3. Anticarcinogenic Activities of Sulforaphane and Structurally Related Synthetic Norbornyl Isothiocyanates (#) Proc Natl Acad Sci USA 1994 Apr 12;91(8):3147-50
Y Zhang, TW Kensler, C Cho, GH Posner and P Talalay PubMed ID: 8159717

COLON CANCER
Researchers at the American Health Foundation, Valhalla, NY, showed that sulforaphane significantly inhibited the formation of colon cancer in rats.

1. Sulforaphane inhibits histone deacetylase in vivo and suppresses tumorigenesis in Apcmin mice (#)
FASEB Journal Express. Published on-line January 11, 2006.
Melinda C. Myzak, W. Mohaiza Dashwood, Gayle A. Orner, Emily Ho, and Roderick H. Dashwood
doi:10.1096/fj.05-4785fje
PubMed ID: 16407454

2. Chemoprevention of colonic aberrant crypt foci in Fischer rats by major isothiocyanates in watercress and broccoli.
Proceedings of the American Association for Cancer Research, March 2000; 41:660.
Chung F-L, Conaway CC, Rao CV, Reddy BS.
PubMed ID: 11133820

3.Sulforaphane, A Naturally Occurring Isothiocyanate, Induces Cell Cycle Arrest and Apoptosis in HT29 Human Colon Cancer Cells
Cancer Research. 2000 March 1; 60(5):1426-1433.
Gamet-Payrastre L, Li P, Lumeau S, Cassar G, Dupont MA, Chevolleau S, Gase N, Tulliez J, Ter�� F.
PubMed ID: 10728709

LIVER
In a rural area of China where there is a very high prevalence of liver cancer due to a confluence of hepatitis virus and environmental toxins, scientists at Johns Hopkins University and Qidong Liver Institute PRC, near Shanghai performed experiments to measure the ability of broccoli sprouts to increase the body's abilities to detoxify carcinogens. The change in these biomarkers strongly suggests that there was an enhanced detoxification (neutralization) of carcinogens from the human body leading to a reduction in cancer risk.

1. Effects of glucosinolate-rich broccoli sprouts on urinary levels of aflatoxin-DNA adducts and phenanthene tetraols in a randomized clinical trial in He Zuo Township, Qidong, PRC
Cancer Epidemiol. Biomarkers Prev., Nov 2005; 14(11).
Kensler, T.W., Chen, J-G., Egner, P.A., Fahey, J.W., Jacobson, L.P., Stephenson, K.K., Ye, X., Coady, J.L.,Wang, J-B., Wu, Y., Sun, Y., Zhang, Q-N., Zhang, B-C., Zhu, Y-R., Qian, G-S., Carmella, S.G., Hecht, S.S., Benning, L., Gange, S.J., Groopman, J.D. and Talalay, P.
PubMed ID: 16284385

LUNG CANCER
In the September 15, 2005 issue of Cancer Research, scientists from the Georgetown University Medical Center, reported that sulforaphane and another isothiocyanate could prevent benign tumors produced by a cigarette carcinogen from developing into full-blown cancer tumors in lungs of mice.
1.Antimetastatic activity of Sulforaphane. Life Science 2006 May 22; 78(26):3043-50.Thejass P, Kuttan G. doi:10.1016/j.lfs.2005.12.038 PubMed ID: 16600309

2. N-Acetylcysteine Conjugate of Phenethyl Isothiocyanate Enhances Apoptosis in Growth-Stimulated Human Lung Cells.
Cancer Res. 2005 Sep 15;65(18):8538-47.
Yang-Ming Yang, Meena Jhanwar-Uniyal, Joel Schwartz, C. Clifford Conaway, H. Dorota Halicka, Frank Traganos and Fung-Lung Chung. PubMed ID: 16166335

3. Phenethyl Isothiocyanate and Sulforaphane and their N-Acetylcysteine Conjugates Inhibit Malignant Progression of Lung Adenomas Induced by Tobacco Carcinogens in A/J Mice. Cancer Res. 65: (18) 8548-8557.
Conaway, C, Wang, C-X, Pittman, B, Yang, Y-M, Schwartz, J, Tian, D, McIntee, E,Hecht, S, Chung, F-L. PubMed ID: 16166336

PROSTATE CANCER
Potent Induction of Phase 2 Enzymes in Human Prostate Cells by Sulforaphane.
Cancer Epidemiology, Biomarkers & Prevention, Vol. 10, pp. 949-954. Sept. 2001.
James D. Brooks, Vincent G. Paton and Genevieve Vidanes.
PubMed ID: 11535546
Human prostate cancer cells responded well to treatment with sulforaphane in the form of broccoli sprout extracts, showing dramatic increases in their Phase 2 protective enzymes.

SKIN CANCER
Topical application of sulforaphane-containing broccoli sprout extracts is a promising strategy for protecting against skin tumor formation after exposure to UV radiation.

1. Protection against UV-light-induced skin carcinogenesis in SKH-1 high-risk mice by sulforaphane-containing broccoli sprout extracts.
Cancer Epidemiology, Biomarkers & Prevention, November 2005, Vol. 14(11).
Dinkova-Kostova, A, Jenkins, S, Fahey, J, Ye, L, Wehage, S, Liby, K, Stephenson, K, Wade, K and Talalay, P. doi:10.1016/j.canlet.2005.09.012 PubMed ID: 16271437

STOMACH CANCER

In a study from Japan, broccoli sprouts were fed to patients infected with Helicobacter pylori bacteria. H. pylori infection can cause stomach ulcers and markedly increases the risk of developing stomach cancer.
1.Daily Intake of Sulforaphane-Rich Broccoli Sprouts Improves Gastritis in H.pylori-Infected Human Subjects. Cancer Epidemiology, Biomarkers & Prevention, November 2005, Vol. 14(11 Part 2): 2754s. Yanaka, A, Zhang, S, Yamamoto, M, Fahey, J.

2. Oral Broccoli Sprouts for the Treatment of Helicobacter pylori Infection: A Preliminary Report Digestive Diseases and Sciences, 49(7/8):1088-1090, 2004.
Mark V. Galan, Md, Arfana A. Kishan, Md, And Ann L. Silverman, Md
doi:10.1023/B:DDAS.0000037792.04787.8a
PubMed ID: 15387326

3. Sulforaphane inhibits extracellular, intracellular, and antibiotic-resistant strains of Helicobacter pylori and prevents benzo[a]pyrene-induced stomach tumors (#)
Proc. Natl. Acad. Sci. USA, Vol. 99, Issue 11, pp. 7610-7615, May 28, 2002
Jed W. Fahey, Xavier Haristoy, Patrick M. Dolan, Thomas W. Kensler, Isabelle Scholtus, Katherine K. Stephenson, Paul Talalay, and Alain Lozniewski
doi:10.1073/pnas.112203099
PubMed ID: 12032331

Our Practitioners

Acupuncture offered by:

Geoff D�Arcy, Lic. Ac.
Betty Woo, Lic. Ac.
Pavel Jalynytchev, Lic. Ac.
Yuanling Liu R.D.,Lic. Ac.

Chiropractic offered by:

Pheng Kouch, D.C.
Wendy Kagan, D.C.

Massage Therapy offered by:

Agnaldo DaCruz, L.M.T.
Judy Fiatorone L.M.T.
Jeni Steward, L.M.T.

Integrative Mind-Body Medicine
Eva Selhub, M.D.

Holistic Pain Management and Detoxification.
Arthur Gertler, M.D.

Psychotherapy
Judy Dempewolff, Ph.D.

Kathy Mongeau, R.Y.T.
Yoga Therapy

Practitioner of the Month

Dr. Gertler M.D.
Dr. Gertler is a board certified internist and gastroenterologist with 30 years of clinical experience. He is a specialist in SCENAR therapy and hands-on healing techniques. By synthesizing a holistic approach to the management of chronic pain he has created a new form of health care which can be integrated into traditional medicine.
Dr. Gertler has enormous experience as a gastroenterologist, yet he can help you through a range of natural therapies. He is available on Mondays at the D.W.C.

Classes & Workshops offered this month at the D.W.C.

Qi Gong
Thursdays 4:30pm
Please call and speak with Betty Woo.

Yoga
Lunch Time Yoga Class: Wednesdays 12:00 noon to 1:00pm
Individual Yoga Therapy Sessions available.
Please call and speak with Kathy Mongeau.

Menopause Group
Please call and speak with Judy Dempewolff.

Schedule your appointment on-line or call your practitioner directly!

Acupuncture Eases Low Back Pain

Researcher recommends the treatment be an option in public health systems

A British study suggests people suffering from low back pain may get at least some added relief from acupuncture compared with standard treatments.
Based on the findings, MacPherson says it would be worthwhile for publicly funded health-care systems to pay for the treatment. "Our recommendation is that routine acupuncture should be provided as an option."

The study involved 241 adults who had been suffering from low back pain for four to 52 weeks. They were randomly assigned to have up to 10 acupuncture sessions over three months, or the usual treatment recommended by their doctor.

People who had received acupuncture were also more likely to report not having needed medication to treat their back pain compared with patients receiving usual care: 68 versus 20, respectively.

The Range of our Clinic and Practitioners

We are proud to offer you a wide range of natural complementary therapies provided by a team of highly skilled practitioners. We can work with you individually or as a co-ordinated team.

▪ ACUPUNCTURE
▪ CHIROPRACTIC
▪ HERBAL MEDICINE
▪ INTEGRATIVE MIND-BODY MEDICINE
▪ HOLISTIC PAIN MANAGEMENT
▪ MASSAGE
▪ PSYCHOTHERAPY
▪ DIETARY COUNSELING

If you are not sure which practitioner or therapy plan is best suited for you, please don�t hesitate to call me and we can discuss the best practitioner/therapy plan possible.

Clinic Director, Geoff D'Arcy 508-652-1975