Super Week Sale: Online orders save an Extra 20% off our everyday discounted 1 to 2 bottle prices. All orders placed online during the Super Week Sale, March 5^th to 11^th, automatically receive an additional 20% off the 1 to 2 bottle price on all products. No discount codes or coupons are needed! Convenience Plan orders receive 25% off the 1 to 2 bottle prices. Learn more about our Convenience Plan Program.

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Example of Super Week Sale Savings:

CoEnzyme Q10, 150mg 60 capsules, Suggested Retail: $74.95
Our Everyday (1-2 bottle) Discount Price: $29.98
Super Week Sale Price, Save an extra 20%: $23.98

Convenience Plan - Always our best price: $22.49

As always, Free Shipping on all U.S. orders over $75!

We've lowered the prices on three of our most popular products including our two most popular CoEnzyme Q10 products!

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• CoEnzyme Q10 is a powerful antioxidant, our body's production of this essential vitamin starts to drop after the age of 30. CoQ10 is necessary for ATP (energy processing) and low levels seem to be a significant contributory factor in cardiovascular disease, declining mental function and other negative health issues. 200mg, 60 softgels or 300mg, 60 capsules Now as low as $39.74!

The US government currently recommends a daily intake of 400IU (International Units) for vitamin D. Both the US government and the European Union have the "tolerable upper intake limit" set at 2000IU. However, in recent years many experts have concluded that both of these levels are far too low. Feeding this controversy, research conducted by the industry trade group, Counsel for Responsible Nutrition found the upper limit could be raised to 10,000 UI.

Two new cancer meta-analysis studies provide more evidence in support of raising the daily intake level for vitamin D. The first of the two studies was published in the American Journal of Preventative Medicine. The study reviewed five colorectal cancer studies with a total of 1448 individuals, all caucasian. Serum (blood) vitamin D levels of the individuals were evaluated and divided into quartiles. The quartiles where then compared to assess relative risk. The researchers found that those in the highest quartile, with serum Vitamin D levels greater than or equal to 33 ng/ml (nanogram per milliliter), had a 50% lower risk than those in the lowest quartile with serum Vitamin D levels, less than or equal to 12 ng/ml. Researchers went on to conclude that if serum vitamin D levels were increased to even greater levels than those found in the study, to 46 ng/ml, colorectal cancer could be reduced by 66%.¹

The authors concluded "the evidence to date suggests that daily intake of 1000-2000 IU per day of vitamin D3 could reduce the incidence of colorectal [cancer] with minimal risk."

The second of the two studies was recently published in the online edition of the Journal of Steroid Biochemistry and Molecular Biology. The study pooled results from two other studies and, as in the colorectal cancer study, subjects were divided into quartiles based on serum vitamin D content. Again relative risk was determined by comparing those in the lowest quartile of serum vitamin D to those in the highest quartile of serum vitamin D. While the range was greater than in the first study, with the lowest quartile of vitamin D being 10 ng/ml or less and the highest being 50 ng/ml or greater, the outcome was similar. The researchers found that those in the highest quartile had a 50% lower risk of breast cancer when compared to those in the lowest quartile.²

The researchers noted that a 50 ng/ml serum level "could be achieved by oral intake of 2000IU per day and, if appropriate and climate allowing, about 12 minutes per day in the noontime sun on a clear day with 50 percent of the skin exposed to the sun."

Learn more about Vitamin D at our website.

The American Cancer Society estimates that nearly 220,000 American men will be diagnosed with prostate cancer in 2007. The American Cancer Society also estimates that 1 in 6 men will get the disease in their lifetime, but only 1 in 34 will die from the disease.

Research published in the American Journal of Clinical Nutrition in January found that elevated selenium intake combined with either higher than average vitamin E or the use of a daily multivitamin may significantly reduce the risk of prostate cancer.³

The researchers, who were from a wide range of institutes in the US and Denmark, studied the serum (blood) selenium levels in 724 men with prostate cancer and 879 healthy control subjects. The men, who were followed for up to 8 years, were part of the larger Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial. The study found that the men who reported a higher than average (28 IU per day) vitamin E intake, who were also in the highest quartile of serum selenium levels, had 42% reduced risk of prostate cancer as compared to those in the lowest quartile of serum selenium levels. Likewise, the researchers found that men who were in the highest quartile of serum selenium, who also reported daily multivitamin use had a 39% reduced risk of prostate cancer. The study did not find that selenium alone was able to affect cancer risk.

Previous studies on selenium have found that it may reduce the risk of prostate and lung cancer as well as stimulate the immune system.

Learn more about our Selenium, Multivitamins and Vitamin E supplements. at our website.

While we often take a good night's sleep for granted, there is more and more research to support the necessity of good quality sleep for sustained health. Recent studies have shown that a lack of sleep can have a dramatic impact on quality of life, influencing one's weight, blood pressure, immune system and, of course, energy levels. All of these may be improved, just by increasing the amount of nightly sleep. For these reasons quality sleep should be as important as exercise and good eating in a healthy lifestyle program.

Weight Gain

Recent research indicates that sleep deprivation can lead directly to weight gain and ultimately, obesity. In one recent study, researchers found that the women sleeping 5 or fewer hours per night were 32% more likely to experience major weight gain, defined as an increase of 33 lbs. or more, and 15% more likely to become obese during the 16-year study period than the women who slept at least 7 hours per night. In addition, women who slept for 6 hours were 12% more likely to have major weight gain and 6% more likely to become obese compared with women who slept at least 7 hours per night. One of the most surprising findings, was that the women who slept less actually ate less as well. Earlier studies have suggested that sleep deprivation may impact the hypothalamus, resulting in reduced the levels of the hormone leptin which gives the sensation of feeling "full" and raising levels of the hormone grehlin which makes us feel hungry.

Blood Pressure

A report published in the May 2006 medical journal Hypertension suggests that long-term sleep deprivation increases the risk of hypertension (high blood pressure). Researchers analyzed data for 4,810 participants, who were between the ages of 32 and 86 years. Among participants between the ages of 32 and 59 years, those who slept less than six hours a night had more than double the risk of high blood pressure than did those who slept more than six hours a night. This association was not significant in participants older than 59 years.

Immune system

Sleep provides a regenerative and rebuilding period for all of your body's systems, especially your immune system. When the body is robbed of this restorative function, it becomes vulnerable to infection and disease. Researchers believe the body releases hormones during sleep that actually boost the immune system. They also believe that the immune system of a well-rested person is more likely to provide a strong defense against invading bacteria and viruses.

Memory

Most of us have had firsthand experience with sleep deprivation and memory reduction. Researchers proved this in a recent study at Harvard Medical School and Boston's Beth Israel Deaconess Medical Center. Researchers kept test subjects awake for 35 hours, exposed them to a series of slides, and then sent them home to sleep. The following day, they exposed subjects to the same slides again, as well as new slides, and asked test subjects to identify which slides were new. Researchers found that the test subjects who had been sleep deprived scored the worst on the slide recognition test when compared to patients who had not been sleep deprived, even though they had been given a full nights sleep prior to the test.

Energy

Energy (or lack of energy) is one of the top 3 health concerns for most adults. Getting good quality sleep is the first step in increasing your energy. Sleep is highly restorative for the body and the mind and if someone doesn't get enough sleep, the body's energy supplies are low for the following day.

Tips for getting a good night's sleep:

Are you getting enough sleep? Experts say that between 7-9 hours is the norm for adults; however, an easy test is whether you find yourself drowsy during the day, even during boring activities. If you do, then you're probably not getting enough sleep. To help improve your sleep, try some of the following tips:

• Go to sleep and wake up at the same time every day, even on weekends.
• Develop a calming ritual to prepare yourself for sleep, whether its drinking caffeine-free herbal tea before bed, meditating, or other relaxing activities.
• Keep a pad and pen by your bed to write down any issues or "to do" list items as they come to you. This helps to alleviate stress.
• Try not to exercise within 3 hours of bedtime as this can be overstimulating and cause insomnia.
• Create a calming bedroom environment- no working, no tv, no bill paying.
• Keep the temperature on the cool side to help you sleep.
• Avoid drinking alcohol before bedtime, as it can rob you of the deep sleep you need during the night.
• Avoid caffeine as it can also prevent deep restful sleep patterns.

1. Gorham, Garland, et al. (2007). "Optimal Vitamin D Status for Colorectal Cancer Prevention." American Journal of Preventive Medicine 32(3): 210-216.

2. Garland, C. F., E.D. Gorham, S.B. Mohr, W.B. Grant, E.L. Giovannucci, M. Lipkin, H. Newmark, M.F. Holick, F.C Garland (2006). "Vitamin D and prevention of breast cancer: Pooled analysis." Journal of Steroid Biochemistry and Molecular Biology doi: 10.1016/j.jsbmb.2006.12.007.

3. Peters, U., C. B. Foster, et al. (2007). "Serum selenium and risk of prostate cancer-a nested case-control study." Am J Clin Nutr 85(1): 209-17.